`Olive Compounds Said to Enhance Healing Power of Human Stem Cells - Olive Oil Times
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Olive Compounds Said to Enhance Healing Power of Human Stem Cells

By Julie Butler
Nov. 6, 2013 11:35 UTC
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A new patent appli­ca­tion high­lights the pos­si­ble use­ful­ness of olive com­pounds hydrox­y­ty­rosol and oleu­ropein in heal­ing wounds.

Including them in com­po­si­tions con­tain­ing human umbil­i­cal cord stem cells reduces the time for a wound to close by about 30 per­cent com­pared to just the cells alone, it is claimed in the appli­ca­tion.

Recently pub­lished by the U.S. Patent and Trademark Office, the appli­ca­tion also says that the amount of retrieved cord blood is expected to increase as physi­cians and expec­tant par­ents become more aware of its poten­tial uses.

Darlene E. McCord is listed as both the inven­tor and appli­cant on the doc­u­ment, ​“Methods for improved wound clo­sure employ­ing Olivamine and human umbil­i­cal vein endothe­lial cells.”

Olivamine is the trade­name for a McCord Research prod­uct that con­tains hydrox­y­ty­rosol and oleu­ropein.

McCord said in the appli­ca­tion that one of the objec­tives of the top­i­cal com­po­si­tion is to sig­nif­i­cantly accel­er­ate wound clo­sure, includ­ing for wounds that tend to resist heal­ing.

Umbilical vein endothe­lial cells are already known to aid wound heal­ing, but adding hydrox­y­ty­rosol and oleu­ropein ​“syn­er­gis­ti­cally enhances wound repair,” she said.

Hydroxytyrosol and oleu­ropein are polyphe­nols found in olives, olive leaves, olive oil and even the waste water from olive oil pro­duc­tion. The com­po­si­tion, how­ever, could use these nat­ural sources or derive its hydrox­y­ty­rosol and oleu­ropein from chem­i­cal syn­the­sis.

“Compositions com­pris­ing hydrox­y­ty­rosol and oleu­ropein may be used to reduce the con­cen­tra­tion of free-rad­i­cals in the cells of skin tis­sue to improve cel­lu­lar func­tion. In addi­tion, com­po­si­tions com­pris­ing suf­fi­cient hydrox­y­ty­rosol and oleu­ropein may be used to induce cells into or main­tain them in a reversible qui­es­cent (dor­mant) state to pro­vide them with time to heal and return to a more viable state with a reduced risk of necro­sis,” she said.

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